What are the differences between L-Citrulline and L-Arginine?

Arginine and citrulline are two amino acids of great interest in the field of sports nutrition and wellness. They have similar effects, but their mechanisms of action and benefits are not quite identical. So, what are the differences between L-Citrulline and L-Arginine?

The description of these two amino acids: L-Citrulline and L-Arginine

L-Arginine

The L-Arginine is a semi-essential amino acid. The body can synthesize it in small quantities, but dietary intake or supplementation may be necessary in certain situations: muscle growth, intense physical effort and sports recovery.

It is also a molecule that promotes the dilation of blood vessels. It contributes to creatine synthesis and protein metabolism, essential for muscles. In addition, L-Arginine helps neutralize ammonia in the cells, which can be the cause of insomnia and other sleep disorders.

L-Citrulline

The L-Citrulline is a non-essential amino acid produced naturally by the body, but also present in certain foods such as watermelon, from which it was first isolated over 70 years ago.

A large quantity of this amino acid is converted to L-Arginine in the body during metabolic processes. L-Citrulline also stands out for its ability to reduce fatigue and support muscle recovery. After intense training, the molecule can promote the elimination of ammonia and other metabolic waste products, while improving blood vessel health.

Key differences between L-Arginine and L-Citrulline

Bioavailability

Arginine is rapidly metabolized in the body, which means it is absorbed more quickly by the body and its organs. Citrulline, on the other hand, is less degraded by the liver and intestines, but helps to transform L-arginine more efficiently in the bloodstream.

Use for sports

Although both acids increase nitric oxide production, Citrulline is often considered more reliable for supporting endurance and continuous performance . Arginine, on the other hand, may be more immediately useful for vasodilation and rapid delivery of nutrients to muscles.

Effects on sleep

L-Arginine is cited for its impact on sleep quality, thanks to its role in eliminating ammonia. Citrulline can also help, as it raises arginine levels in the body.

Recovery benefits

While arginine plays a role in protein synthesis and muscle growth, Citrulline seems to stand out in reducing post-workout fatigue and soreness, as it increases recovery by 40%.

Can L-Citrulline and L-Arginine be mixed?

L-Citrulline can be combined with L-Arginine to enhance the benefits for metabolism, bone preservation and muscle strengthening. This synergy is based in particular on their joint role in the production of nitric oxide, which supports blood circulation and the supply of nutrients to tissues (bone and muscle). This is what we propose in our energizing powder.

In addition, L-Citrulline enhances the efficacy of L-Arginine by increasing its level in the blood, enabling prolonged action on vasodilation and muscle regeneration.

This combination can be particularly interesting for those seeking both improved endurance and recovery after training.

The synergy of these molecules also proves beneficial in supporting muscle building and overall good health, minimizing fatigue and promoting cell regeneration. However, as with any supplementation, it is advisable to consult a health professional to adapt doses to individual needs.

L-Arginine and L-Citrulline are two closely related acids.

• Arginine can be an interesting choice for promoting vasodilation, sleep, hair growth and the release of hormones linked to muscle growth.
• Citrulline, on the other hand, is highly effective in supporting endurance, reducing fatigue and improving recovery after exercise. Their combination can be particularly interesting.